THE FONTAN CIRCULATION

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The Fontan Circulation

The original Fontan procedure was first introduced in the 1970s. The concept behind this surgical technique was revolutionary. It has subsequently transformed the lives of children born with complex congenital heart disease which was once thought to be inoperable and resulted in early death. The procedure itself has had several modifications over the decades, with subsequent improvements in lon...

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The Fontan circulation.

Correspondence to: Professor Marc Gewillig, Pediatric Cardiology, Gasthuisberg University Hospital, B 3000 Leuven, Belgium; marc.gewillig@ uzleuven.be _________________________ A normal mammal cardiovascular system consists postnatally of a double—pulmonary and systemic—circuit, connected in series, powered by a double pump—the ‘‘right’’ and ‘‘left’’ heart. Many complex cardiac malformations ar...

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Biomarkers and the Fontan Circulation.

A lthough the dramatically improved survival of children with single-ventricle heart disease with Fontan circulation in the recent era is a tremendous accomplishment in pediatric cardiology and cardiac surgery, it has been accompanied by a growing realization that Fontan circulation is largely a state of compensated heart failure at risk for decompensation. Fontan failure occurs in numerous way...

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Pathophysiology of the Fontan Circulation

Case Presentation A 15-year-old boy with hypoplastic left heart syndrome presents with newonset abdominal swelling and pretibial edema. The patient has been previously without symptoms from the cardiovascular perspective but is not very active and does not participate in sports. He is growing poorly, with height and weight <5th percentile for age, and has no signs of puberty (Tanner stage 1). B...

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Fontan circulation: the search for targeted therapy.

T he Fontan operation has been the final palliation for children born with congenital heart defects with a functional single ventricle for >4 decades. In the early days of the Fontan operation, focus was rightly on technical modifications and alterations in strategy in an attempt to decrease morbidity and mortality related to the operation itself. 3 In recent years, that focus has shifted towar...

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ژورنال

عنوان ژورنال: Heart

سال: 2005

ISSN: 1355-6037

DOI: 10.1136/hrt.2004.051789